1. | ACUTE CORONARY SYNDROME: PREVALENCE AND MANAGEMENT IN A TERTIARY CARE HOSPITAL IN PALAKKAD |
| Anusha.M, Thangamani. S, Anoop Gopinathan |
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The prevalence of acute coronary syndrome (ACS) among Coronary Artery Disease patients (CAD) are not well studied in Kerala. The study was aimed to access the prevalence and management of ACS among CAD patients in a tertiary care hospital in Palakkad. Methods: A hospital based prospective study was conducted in Rajeev Gandhi Cooperative Multispecialty hospital in Palakkad from July 2022 to January 2023, 90 patients with Acute Coronary Syndrome were included. Details regarding socio-demographic characters, diagnosis, treatment and class of drugs prescribed were noted. Results: 150 Coronary Artery Disease (CAD) patients were included in the study, of which 90 were diagnosed with Acute Coronary Syndrome (ACS) among which 19 (21%)patients were diagnosed with unstable angina,46(51%) with ST Elevation Myocardial Infarction(STEMI) and 25(28%) with Non ST Elevation Myocardial Infarction(NSTEMI).Single vessel disease was the most commonly observed condition 57(63%) and most commonly involved artery was left anterior descending artery57(63%).Drugs prescribed for management of ACS are antiplatelet, antihypertensive, hypoglycemic, statins and antianginal drugs. Conclusion: Recent epidemiological trend of ACS is progressing and it constitutes an important challenge for both patient and treating physician. Patients with ACS are mainly males and SVD is more common and commonly prescribed drug is antiplatelet
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2. | COMMUNITY PHARMACIES AND MALARIA FEVER: A THREAT
TO RATIONAL DRUG PRESCRIPTIONS |
| Krupa B*, Rajani Gunnam, Ramya CH, Sana MD, Hamza SD |
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In community pharmacies located in Chennai, case management for uncomplicated malaria fever will be documented. By
simulating simulated patient visits at community pharmacies in Chennai, a comparative, cross-sectional study was designed to
investigate the management of uncomplicated malaria fever. In 119 randomly selected pharmacies, simulated malaria cases
were prescribed and advice was sought. In addition to taking a history and providing advice and information, the pharmacy's
management was assessed. To compare different types of dispensers at community pharmacies located in different areas with
each other, Kruskal-Wallis and Mann-Whitney U tests were performed. Salesmen handled 74.8% of simulated patients (89
people), pharmacists handled 5.4% of the patients (six people) and diploma holders handled 19.8% of the patients (24 people).
Only a few cases of malaria were treated according to standard treatment guidelines in 83,1 % of the visits (n=99). The
simulated patients were referred directly to physicians in 14.8% (n=18) of cases. It was observed that there are no significant
differences in the way a pharmacist, pharmacy assistant, pharmacy diploma holder, or salesman takes their history and
provides advice. The process of taking histories was more frequently conducted by pharmacists at community pharmacies if
they were available. Among community pharmacies located in a variety of locations (e.g. next to a hospital/supermarket/small
market), no significant differences were observed in the absence of malaria fever in the case management (history taking and
advice). A study found that community pharmacies were not implementing standard treatment guidelines for uncomplicated
malaria fever according to the findings of the study. Untrained pharmacists were treating patients without understanding
referral procedures at community pharmacies. The pharmacists at community pharmacies were more likely to take history, but
they were not very accessible
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3. | ASSESSING ADHERENCE TO DIABETES MEDICATION THERAPY
MANAGED BY PHARMACISTS |
| Rajani Gunnam*, Ramya CH, Sana MD, Hamza SD, Krupa B |
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There are several microvascular and macrovascular complications that are associated with diabetes such as retinopathy,
nephropathy, and myocardial infarction, which can be prevented or delayed if the patient adheres to prescribed medication
regimens. Pharmacist-managed DMTAC program is intended to improve patient medication adherence, glycaemic control,
and lipid parameters. Data were extracted from patients who had completed eight pharmacy visits and had glycosylated
haemoglobin (HbA1c) >8%. A review of patient records and DMTAC forms was conducted in order to obtain demographic
information, medications regimens, adherence, laboratory parameters, and pharmacists' interventions. The results of the study
examined HbA1C levels, fasting blood glucose levels, low-density lipoprotein cholesterol levels, triglyceride levels and highdensity lipoprotein cholesterol levels. Patients' medication adherence data were also evaluated MMMAS; high affiliation was
defined as scores >8, medium adherence as scores 6 to 8, and low adherence as scores less than 6. Among the 43 patients
included in the study, 53.5% were females; 46.5% were TamilNadu, 44.2% were Karnata, and 9.3% were Kerala. We
achieved a mean reduction in HbA1c of 1.73 percent (p0.001), a mean reduction in fasting blood glucose of 2.65 millimol/l
(p=0.01), and a mean shorten in low-density lipoprotein cholesterol of 0.38 millimol/l (p=0.007). HDL cholesterol and TG
cholesterol did not differ significantly. The mean MMMAS score for patients improved significantly after the completion of
the DMTAC program from 7.00 to 10.84 (p 0.001). Efforts to improve HbA1c, glucose, LDL cholesterol, and medication
adherence in diabetic patients through significant improvements were achieved as a result of the pharmacy-managed DMTAC
program
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