1. | REVIEW ON ANTI-VIRAL AND ANTI-BACTERIAL ACTIVITY STUDY ON EXTRACTS OF BERRIES OF SOLANUM TORVUM |
| D.Nandhini, G.Navina, L.Predeepa, T.Pavithra, A.Priya, J.Karthi |
|
|
|
Solanum torvum commonly known as turkey berry is found in tropical Africa, Asia, South America. Methanolic and ethanolic extracts of berries of Solanum torvum SW. were evaluated in vitro for antiviral and antibacterial activity by disc diffusion method comparing zone of inhibition with that of standard such as acyclovir and amikacin, respectively. The extracts of berries of solanum torvum contains number of potentially and pharmacologically active phytoconstituents including flavonoids, phenols, tannins, saponins, steroids, alkaloids. A new steroidal glycoside named torvoside(H) also found to exhibit antiviral activity (HSV-1). The minimum concentration that inhibits bacterial activity using ethanolic extracts was 9.6 to 19.2μg/ml . Results revealed that fruit extracts showed significant activity due to presence of phytoconstituents. Thus, solanum torvum has antimicrobial activity can be used clinically to find novel antibacterial and antiviral compounds..
|
2. | FORMULATION AND INVIVO INVESTIGATION OF POLYHERBAL ANTI-DIARRHOEAL SYRUP |
| N. Deepa*, R.Kaviselvan, E.Prithivirajan, S.Dhanapriya, S.Krishna, N.Ram Vignesh |
|
|
|
Diarrhoea is the common disease mostly seen in developing countries. It is caused by contaminated food, variety of virus, and bacteria and parasitic organisms. 70% of acute diarrhoaea is due to food borne disease. Chronic diarrhoea is caused by inflammatory bowel disease, microscopic collitis. The antibiotics and their resistance are used for the bacteria clostridium difficile which increases the diarrheal incidence. Herbal medicines are used mostly on india and plays important role in the world. Plants consist of astringent properties, anti-inflammatory properties, and also bulk forming agents are used for the treatment of diarrhea. The SYRUP showed marked reduction in the number of diarrhoea stools and the reduction in the weight and volume of the intestinal contents, as well as a modest reduction in intestinal transit. This study did not go further, to demonstration as to whether the extract altered the activity of Na/K ATPase or activation of chloride channels
|
|